The Automated Refinement Procedure, ARP/wARP is a program package for protein structure refinement. It combines in an iterative manner reciprocal space structure factor refinement with updating of the model in real space. The latter attempts to mimic and automate a typically time extensive model rebuilding session at the graphics. The real space update utilises some general properties of the electron density synthesis as well as stereo-chemical criteria. The ARP/wARP suite is under continuous development.
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